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Curcumin can not only reduce the production of uric acid by inhibiting the activity of XO, alleviating the symptoms of hyperuricemia and gout to a certain extent [443, 444], but also inhibit the activity of inducible nitric oxide synthase, reducing the production of NO [445, 446]
Lightly cooking broccoli instead of fully cooking also increases the sulforaphane levels.[ref] Safety, timing, and dosage of sulforaphane supplements: As a natural part of cruciferous vegetables, sulforaphane is generally regarded as safe in low doses
Sometimes, such alterations usually lead to mutations and genetic instability, which may subsequently lead to cancer [104]
[DOI] [PubMed] [Google Scholar] 29.Ye P., DErcole A.J